Remco L.A de Vrueh : rechercher sur Z-Library

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1

Deal watch: Roles and strategies for health foundations in public–private partnerships

de Vrueh, Remco L., Awad, Waseem, Stolk, Anne, Dijcks, Fred A., Rijnders, Ton W.M., Janssen, Jorg W.

Journal:

Nature Reviews Drug Discovery

Année:

2014

Langue:

english

Fichier:

PDF, 596 KB

english, 2014

2

Does market exclusivity hinder the development of Follow-on Orphan Medicinal Products in Europe?

Anne EM Brabers, Ellen HM Moors, Sonja van Weely, Remco LA de Vrueh

Journal:

Orphanet Journal of Rare Diseases

Année:

2011

Langue:

english

Fichier:

PDF, 191 KB

english, 2011

3

Drug development for exceptionally rare metabolic diseases: challenging but not impossible

Putzeist, Michelle, Mantel-Teeuwisse, Aukje K, Wied, Christine C Gispen-de, Hoes, Arno W, Leufkens, Hubert GM, de Vrueh, Remco LA

Journal:

Orphanet Journal of Rare Diseases

Année:

2013

Langue:

english

Fichier:

PDF, 265 KB

english, 2013

4

Towards harmonization of outcome measures in children with mitochondrial disorders

Koene, Saskia, Jansen, Merel, Verhaak, Chris M., de Vrueh, Remco L.A., de Groot, Imelda J.M., Smeitink, Jan A.M.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 49 KB

english, 2013

5

Predictors of orphan drug approval in the European Union

Harald E. Heemstra, Remco L. de Vrueh, Sonja van Weely, Hans A. Büller, Hubert G. M. Leufkens

Journal:

European Journal of Clinical Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 158 KB

english, 2008

6

Cryopreservation Enables Long-Term Storage of 9-(2-Phosphonylmethoxy-ethyl) Adenine Prodrug-Loaded Reconstituted Lactosylated High-Density Lipoprotein

Remco L. A. de Vrueh, Theo J. C. van Berkel, Martin K. Bijsterbosch

Journal:

Pharmaceutical Research

Année:

2001

Langue:

english

Fichier:

PDF, 169 KB

english, 2001

7

5′-Amino Acid Esters of Antiviral Nucleosides, Acyclovir, and AZT Are Absorbed by the Intestinal PEPT1 Peptide Transporter

Hyo-kyung Han, Remco L. A. de Vrueh, Julie K. Rhie, Kuang-Ming Y. Covitz, Philip L. Smith, Chao-Pin Lee, Doo-Man Oh, Wolfgang Sadee, Gordon L. Amidon1

Journal:

Pharmaceutical Research

Année:

1998

Fichier:

PDF, 489 KB

1998

8

Synthesis of a Lipophilic Prodrug of 9-(2-Phosphonylmethoxyethyl)adenine (PMEA) and Its Incorporation into a Hepatocyte-Specific Lipidic Carrier

Remco L. A. de Vrueh, Erik T. Rump, Leo A. J. M. Sliedregt, Erik A. L. Biessen, Theo J. C. van Berkel, Martin K. Bijsterbosch

Journal:

Pharmaceutical Research

Année:

1999

Fichier:

PDF, 1.44 MB

1999

9

Orphan drug development across Europe: bottlenecks and opportunities

Harald E. Heemstra, Remco L.A. de Vrueh, Sonja van Weely, Hans A. Büller, Hubert G.M. Leufkens

Journal:

Drug Discovery Today

Année:

2008

Langue:

english

Fichier:

PDF, 377 KB

english, 2008

10

Translation of rare disease research into orphan drug development: disease matters

Harald E. Heemstra, Sonja van Weely, Hans A. Büller, Hubert G.M. Leufkens, Remco L.A. de Vrueh

Journal:

Drug Discovery Today

Année:

2009

Langue:

english

Fichier:

PDF, 399 KB

english, 2009

11

Modification of the plasma clearance and liver uptake of steroid ester-conjugated oligodeoxynucleotides by association with (lactosylated) low-density lipoprotein

Erik T Rump, Remco L.A de Vrueh, Muthiah Manoharan, Ingrid H.E Waarlo, Richard van Veghel, Erik A.L Biessen, Theo J.C van Berkel, Martin K Bijsterbosch

Journal:

Biochemical Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 541 KB

english, 2000

12

Recombinant lipoproteins: lipoprotein-like lipid particles for drug targeting

Patrick C.N Rensen, Remco L.A de Vrueh, Johan Kuiper, Martin K Bijsterbosch, Erik A.L Biessen, Theo J.C van Berkel

Journal:

Advanced Drug Delivery Reviews

Année:

2001

Langue:

english

Fichier:

PDF, 922 KB

english, 2001

13

Selection of development candidates based on in vitro permeability measurements

Chao-Pin Lee, Remco L.A. de Vrueh, Philip L. Smith

Journal:

Advanced Drug Delivery Reviews

Année:

1997

Langue:

english

Fichier:

PDF, 1.45 MB

english, 1997

14

Safety-Related Regulatory Actions for Orphan Drugs in the US and EU

Harald E. Heemstra, Thijs J. Giezen, Dr Aukje K. Mantel-Teeuwisse, Remco L. A. de Vrueh, Hubert G. M. Leufkens

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 230 KB

english, 2010

15

Preparation of Conjugates of Oligodeoxynucleotides and Lipid Structures and Their Interaction with Low-Density Lipoprotein

Rump, Erik T., de Vrueh, Remco L. A., Sliedregt, Leo A. J. M., Biessen, Erik A. L., van Berkel, Theo J. C., Bijsterbosch, Martin K.

Journal:

Bioconjugate Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 154 KB

english, 1998

16

Lipophilic Derivatization of the Antiviral Drug 9-(2-Phosphonylmethoxyethyl)adenine and Its Incorporation into a Lactosylated Lipid Carrier to Improve Its Liver Uptake

de Vrueh, Remco L.A., Rump, Erik T., Biessen, Erik A.L., Balzarini, Jan, van Berkel, Theo J.C., Bijsterbosch, Martin K.

Journal:

Nucleosides and Nucleotides

Année:

1997

Langue:

english

Fichier:

PDF, 191 KB

english, 1997

17

Modification of a Phosphorothioate Oligonucleotide with Cholesterol Induces Association of the Oligonucleotide to Serum Lipoproteins and Affects Its Biological Fate

Bijsterbosch, Martin K., Manoharan, Muthiah, Tivel, Kathleen L., Rump, Erik T., Biessen, Erik A.L., De Vrueh, Remco L.A., Cook, P. Dan, van Berkel, Theo J.C.

Journal:

Nucleosides and Nucleotides

Année:

1997

Langue:

english

Fichier:

PDF, 224 KB

english, 1997

18

Conjugation of Oligonucleotides with Steroid Structures and Their Interaction with the Low-Density Lipoprotein

Rump, Erik T., de Vrueh, Remco L.A., Biessen, Erik A.L., van Berkel, Theo J.C., Bijsterbosch, Martin K.

Journal:

Nucleosides and Nucleotides

Année:

1997

Langue:

english

Fichier:

PDF, 191 KB

english, 1997

19

Targeting Hepatitis B Therapy to the Liver

Dr Patrick C. N. Reusen,Remco L. A. de Vrueh…

Journal:

Clinical Pharmacokinetics

Année:

1996

Langue:

english

Fichier:

PDF, 3.92 MB

english, 1996

20

Towards the harmonization of outcome measures in children with mitochondrial disorders

Koene, Saskia, Jansen, Merel, Verhaak, Chris M, De Vrueh, Remco LA, De Groot, Imelda JM, Smeitink, Jan AM

Journal:

Developmental Medicine & Child Neurology

Année:

2013

Langue:

english

Fichier:

PDF, 262 KB

english, 2013

21

Product development programs for neglected tropical diseases: A crucial role for expert meetings

Hussaarts, Leonie, van der Weijde, Kim, Dome, Pierre, Kourany-Lefoll, Elly, Reinhard-Rupp, Jutta, de Vrueh, Remco, Flisser, Ana

Journal:

PLoS Neglected Tropical Diseases

Année:

2017

Langue:

english

Fichier:

PDF, 490 KB

english, 2017

22

Editorial: Public-Private Partnerships as Drivers of Innovation in Healthcare

de Vrueh, Remco L. A., de Vlieger, Jon S. B., Crommelin, Daan J. A.

Journal:

Frontiers in Medicine

Année:

2019

Fichier:

PDF, 728 KB

2019